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This chapter instructs you how to interpret the labels on chemical containers, and how to safely store chemicals in the laboratory in a way that minimizes incompatible chemical reactions, spillage, breaking, or waste due to expiration.

This chapter discusses the major routes of exposure to chemical substances during laboratory work, and several safe handling practices that can minimize your risk while working with chemical substances. The last section lists practices for the safe use of hydrofluoric acid.

Planning and implementation of control practices for the prevention of occupationally acquired cancer and for the protection of the general environment is to be included in all research programs involving known or suspected chemical carcinogens.

The University of North Carolina at Chapel Hill (UNC-CH) Nephropathology Laboratory is committed to ensuring that laboratory employees are provided a safe working environment free from unnecessary hazards. All laboratory employees have a right to know about health hazards present in their work-place in order to make safe, knowledge-able decisions about any personal risks associated with their daily work activities.

As a generator of hazardous waste, the University is required to comply with federal standards promulgated by the Environmental Protection Agency (EPA) and the Department of Transportation (DOT). These regulations require documentation of the transfer of hazardous waste from the point of generation to it’s final disposal.

This chapter provides resources that can help you prevent a laboratory accident due to mishandling explosive substances, or mixing incompatible reactive substances. This chapter details several specific examples of explosive and reactive hazards that are common in laboratories.

This chapter supplements previous chapters by giving specific extra precautions, postings, training, and protective equipment necessary when working with substances that are highly toxic and/or select carcinogens. The appendices at the end of the chapter are a thorough (but not exhaustive) list of substances that might be present in your lab that are highly toxic and/or carcinogenic.

The use and storage of hazardous chemicals potentially pose threats to the environment, health and safety of employees and citizens at large as evidenced by events such as the methyl isocyanate gas release in Bhopal, India. The threat is especially great for fire and emergency response workers and potentially severe for employees and citizens in the vicinity of bulk storage facilities.

This chapter describes the hazards associated with peroxide formation in chemical compounds, methods to detect peroxides, safe handling, use, and storage of peroxidizable compounds, and how to remove peroxide contamination from chemicals.

The standards described provide guidance to all researchers and animal handlers administering chemical agents, whether they be pharmaceutical or non-pharmaceutical grade.

OSHA 1910.1450, “Occupational Exposures to Hazardous Chemicals in Laboratories” (henceforth referred to as the Laboratory Standard) dictates that employers limit employees’ exposure to hazardous chemicals to below the permissible exposure limit (PEL) (or action level, if applicable) for a specific chemical.

The provisions of the NC OSHA Hazard Communication Program were revised and became law in March 2012 to encompass global harmonization. The HAZCOM 2012 Standard requires employers to provide employees with information concerning the hazards associated with the chemicals in their workplace. This standard requires a written hazard communication program, container labels, inventory of chemicals, area warning signs, safety data sheets, and chemical safety training and information sessions.

The characterization, management storage and disposal of laboratory wastes (i.e., chemical waste including hazardous and non-hazardous solid waste, radioactive or mixed waste, biohazardous and medical waste, and universal waste) is regulated and requires strict compliance with regulatory obligations.

This chapter outlines some of the basic regulations that govern laboratory safety, services offered by EHS, how to report injuries and incidents, laboratory self-inspections, and how to respond to fires and chemical spills.

The University of North Carolina at Chapel Hill (University) is committed to providing students, faculty and staff with engineering controls that minimize their exposure to hazardous materials. This policy addresses the installation, removal, change, and monitoring of ducted and non-ducted equipment used to control exposure to chemicals, toxins, radionuclides, and biohazard agents at the University.