Radiation Safety Manual - Chapter 13: Animal Handling Procedures

Title

Radiation Safety Manual - Chapter 13: Animal Handling Procedures

General

Projects involving administration of radionuclides to animals require information on specific arrangements for housing the animals during the project. Information required includes:

  1. The kind and number of animals to be used in the study (# per experiment + total # of experiments).
  2. The radionuclide to be administered per animal and how administered.
  3. The ultimate fate of the animal and suspected excretion rate of the radionuclide.
  4. Instructions for handling and monitoring of the animals and proposed method of disposal of the animal and excreta. These instructions shall be posted in the animal housing area.

If the total amount of administered nuclide per experiment exceeds the quantity found in the N.C. Regulations for Protection Against Radiation, Exempt Quantities Table, then the animals must be housed in areas designed for hazardous materials as assigned by the Director of Division of Comparative Medicine (DCM; formerly the Division of Laboratory Animal Medicine (DLAM)). Special handling instructions are to be forwarded to the animal care personnel and posted prior to administering the radionuclide to the animals.

If the total amount of administered nuclide per experiment is less than the quantity posted in the Exempt Quantities Table, then arrangements can be made to house the animals in any area approved by the Director of Laboratory Animal Medicine and the Radiation Safety Officer. Such low-level studies may be conducted in approved laboratories when the animal survival time does not exceed 12 hours. Longer survival times require DCM housing. A "Use of Radioactive Materials in Laboratory Animals" Form (this form is accessed through the ACAP web application) must be submitted to and approved by the EHS before space can be assigned in the DCM isolation facilities.

Specific Requirements:

  1. Cages or isolation units are to be designated as radioactive use areas.
  2. Bedding and excrement are to be collected as radioactive waste. Contact the Hazardous Waste Section in the EHS, for waste packaging information.
  3. Cages are to be cleaned and surveyed at the end of each individual experiment. Survey records are to be maintained by the Authorized User.
  4. The DCM must be notified of the need for cages to be used in studies with radionuclides. Contact DCM for assistance.

Back to Chapter Twelve

Proceed to Chapter Fourteen

Details

Article ID: 132064
Created
Thu 4/8/21 9:23 PM
Modified
Sun 7/3/22 11:57 AM
Effective Date
If the date on which this document became/becomes enforceable differs from the Origination or Last Revision, this attribute reflects the date on which it is/was enforcable.
10/02/2020 10:20 AM
Issuing Officer
Name of the document Issuing Officer. This is the individual whose organizational authority covers the policy scope and who is primarily responsible for the policy.
Issuing Officer Title
Title of the person who is primarily responsible for issuing this policy.
Executive Director
Last Review
Date on which the most recent document review was completed.
10/02/2020 10:20 AM
Last Revised
Date on which the most recent changes to this document were approved.
12/20/2018 11:00 PM
Next Review
Date on which the next document review is due.
09/01/2025 12:00 AM
Origination
Date on which the original version of this document was first made official.
04/01/2014 12:00 AM
Responsible Unit
School, Department, or other organizational unit issuing this document.
Environment, Health and Safety