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Management of sponsored research is a combined effort of the University of North Carolina System Office (UNC-SO), the University proper, the sponsors that provide their support to research efforts at the University, and the Principal Investigators (PIs) who spearhead the research itself. The Office of Sponsored Programs (OSP) considers the policies, regulations, and requirements issued by State, University, and Federal offices for every individual sponsored research project.

Formaldehyde is a colorless, highly toxic, and flammable gas at room temperature. It is a strong smelling chemical which is commonly used in research and medical laboratories as an aqueous solution. This document establishes procedures for the safe handling and use of formaldehyde, formalin, and paraformaldehyde solutions used in perfusions.

Isoflurane is a halogenated anesthetic gas commonly used in University animal research facilities and individual laboratories. This document establishes procedures for the safe handling and use of 1-chloro-2,2,2-trifluoroethyl difluoromethyl ether (CAS# 26675-46-7), commonly known as isoflurane or Forane®.

The standards and procedures described in this document provide guidance to all researchers and animal handlers for the environmental enrichment of research animals.

This document establishes procedures for the safe handling and use of urethane (CAS# 51-79-6). Urethane is an anesthetic commonly used alone or in combination with other drugs in university animal research facilities and individual laboratories.

This document establishes procedures for the safe handling and use of Tamoxifen (CAS# 10540-29-1). Tamoxifen is a white, odorless, crystalline solid with a melting point of 140-144 degrees Celsius. It is an antineoplastic agent used to treat breast cancer and is used in campus laboratories and animal facilities for cancer research studies.

This document establishes procedures for the safe handling and use of ethyl 3-aminobenzoate methanesulfonate (CAS# 886-86-2), commonly known as MS-222 or Tricaine methanesulfonate. Pharmaceutical grade MS-222 is also available (e.g., Finquel® and Tricaine-S®).

The purpose of this directive is to explain how department planning and research functions are performed and to assign responsibilities. It is the policy of the University of North Carolina at Chapel Hill Police Department (UNC-CH PD) to provide effective agency management through various planning and research activities. The department works closely with the University administration to meet the needs of the community it serves.

enter new SOP per Bryant Hutson's email

This document establishes procedures for the safe handling and use of 7,12-dimethylbenz(a)anthracene, commonly known as DMBA (CAS# 57-97-6) in university Division of Comparative Medicine (DCM; formerly the Division of Laboratory Animal Medicine (DLAM)) facilities. DMBA is a highly potent carcinogen that causes cancer and heritable genetic damage and is used to induce cancer in animal models.

This document sets forth the standards of research conduct expected of members of the research community at The University of North Carolina at Chapel Hill, consistent with the Research Code of Conduct Policy.

Chloroform (CAS 67-66-3) is commonly used in laboratories during DNA purification procedures in biology and biochemistry and also as a solvent in organic synthesis. Chloroform is a clear, colorless, nonflammable, volatile liquid with a pleasant sweet odor. This document establishes procedures for the safe handling and use of chloroform.

This document establishes a procedure for the safe handling and use of streptozotocin, commonly known as STZ (CAS# 18883-66-4), in the university Division of Comparative Medicine (DCM) large animal facilities. STZ is a flammable solid and suspected of causing genetic defects and cancer. STZ is commonly used to induce diabetes in animals. It is a non-volatile solid and inhalation of dust should be prevented.

This document establishes procedures for the safe handling and disposal of Ethidium Bromide (CAS# 1239-45-8, commonly abbreviated EtBr). Ethidium bromide is frequently used in molecular biology laboratories as a nucleic acid stain due to its ability to intercalate DNA and its fluorescent properties when exposed to ultraviolet light.

This document establishes procedures for the safe handling and use of Tetrodotoxin. Tetrodotoxin is an extremely potent poison (toxin) found mainly in the liver and sex organs (gonads) of some fish, such as puffer fish, globefish, and toadfish (order Tetraodontiformes) and in some amphibian, octopus, and shellfish species. Human poisonings commonly occur when the flesh and/or organs of the fish are improperly prepared and eaten.