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The standards and procedures described below provide guidance regarding expectations for Institutional Animal Care and Use Committee (IACUC) member participation at the University of North Carolina at Chapel Hill ("UNC-Chapel Hill" or "University").
The standards and procedures described in this document provide guidance to all researchers and animal handlers for managing potential weight loss that may occur due to experimental variables or conditions that could interfere with eating and / or drinking (e.g. difficulty with ambulation).
The standards and procedures described in this document provide guidance to all researchers and animal handlers utilizing adjuvants for antibody production with a special emphasis on Freund ’s adjuvant. This standard is adopted from National Institutes of Health (NIH) Office of Animal Care and Use’s (OACU) Guide.
The standards and procedures described in this document provide guidance to all researchers and animal handlers for requirements for humane endpoints for mice and rats in cancer studies.
This document is intended to describe aseptic technique for amphibian oocyte harvesting survival surgeries. This Standard allows for five survival surgeries and one non-survival surgery to be performed on a single amphibian.
This document serves to describe the University’s Standards for creating and maintaining aseptic conditions during survival procedures in USDA covered species, while also providing a standard for the pre and post-operative management.
The standards and procedures described in this document provide guidance to all researchers and animal handlers for the establishment and maintenance of a Satellite Animal Facility.
The standards and procedures described in this document provide guidance to all researchers and animal handlers for ensuring adequate aseptic technique for all non-USDA regulated rodent (i.e., mice and rats) survival surgeries.
The standards and procedures described in this document provide guidance to all researchers and animal handlers regarding the humane endpoints for laboratory rodents utilized in research, teching, or testing.
The purpose of this standard is to ensure that any proposed neuromuscular blocking drugs are properly utilized in conjunction with appropriate analgesics and anesthetics and users are aware of autonomic nervous system changes that can be indicator of pain related to an inadequate depth of anesthesia.
This document is intended to ensure sufficient space for mice with litters that will allow pups to develop to weaning without detrimental effects, and to house adult mice in space that is sufficient for their needs. This Standard is a blend of the requirements in the 8th edition of the Guide for the Care and Use of Laboratory Animals and the long-standing, performance-based UNC policy.
The standards and procedures described in this document provide guidance to all researchers and animal handlers regarding identification of pain in animals and appropriate analgesia for post-operative and Pain Category D procedures to prevent pain.
This document is intended to provide uniform guidance to researchers in the preparation, storage and use of Tribromoethanol.
The standards and procedures described in this document provide guidance to all researchers and animal handlers for the euthanasia of rodents. Performing euthanasia correctly is an ethical imperative. Proper euthanasia minimizes pain/distress and reliably causes death. This document does not contain details for conduct of certain procedures.
The purpose of this Standard is to ensure sufficient space for rats with litters that will allow pups to develop to weaning age without detrimental effects, and to house adult rats in space that is sufficient for their needs.