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This chapter gives definitions and protocols for chemicals that are classified as controlled substances by the U.S. Drug Enforcement Administration. Controlled substances have special rules for acquisition, storage, security, inventory/recordkeeping, disposal, and importing or exporting, detailed in this chapter. The appendices include a current list of controlled substances and forms for inventory support and personnel screening.

The Occupational Safety and Health Administration (OSHA) issued a standard (29 CFR 1910.1048) to ensure proper protection of all workers exposed to formaldehyde. The standard applies to all forms of formaldehyde including gas, aqueous solutions, solids, and materials that can release it.

This chapter covers the hazards associated with laboratory animal handling, mandatory and recommended control practices, the institutional structures that UNC-Chapel Hill has in place to assure animal welfare, and requirements for using hazardous agents in laboratory animals.

This chapter lists and describes several major categories of hazardous materials and/or hazardous operations that you could work with in your lab. For each category, the chapter includes recommended safe work practices and regulatory requirements (if applicable).

This chapter discusses the major routes of exposure to chemical substances during laboratory work, and several safe handling practices that can minimize your risk while working with chemical substances. The last section lists practices for the safe use of hydrofluoric acid.

This chapter describes the various types of protective equipment and clothing that can protect you while working in the lab. Details for safe use, care, and acquisition are given for eye/face protection, gloves, lab apparel, foot protection, and respiratory protection.

The characterization, management storage and disposal of laboratory wastes (i.e., chemical waste including hazardous and non-hazardous solid waste, radioactive or mixed waste, biohazardous and medical waste, and universal waste) is regulated and requires strict compliance with regulatory obligations.

This chapter is an overview of the requirements for working with biological hazards. You can find more detailed information about working with biological hazards in the UNC Exposure Control Plan (Bloodborne Pathogens), the UNC Biological Safety Manual and on our website.

This chapter describes the hazards associated with peroxide formation in chemical compounds, methods to detect peroxides, safe handling, use, and storage of peroxidizable compounds, and how to remove peroxide contamination from chemicals.

This chapter outlines the properties of flammable liquids, solids, and gases, the proper storage and use of flammable substances, and the properties of fire extinguishers.

This chapter instructs you how to interpret the labels on chemical containers, and how to safely store chemicals in the laboratory in a way that minimizes incompatible chemical reactions, spillage, breaking, or waste due to expiration.

This chapter describes the containment principles of biological safety cabinets (BSCs), the various classes and types of BSCs and their uses, how to select the correct type of BSC for your needs, how to get approval for installation of a BSC, and their installation and certification requirements.

The concern of the University of North Carolina at Chapel Hill (“University”) for laboratory safety extends not only to employees but also to any persons visiting University laboratories, especially high school students and minors under the age of 18, who may potentially be exposed to hazardous materials. Laboratories are common sources of thermal dangers, compressed gases, electrical hazards, chemical, biological, and radioactive materials, lasers, and sharp objects.

To ensure that research laboratory freezer alarm systems (freezer alarms) are functional and compatible with existing monitoring equipment, this policy establishes guidelines for all university departments relating to the request for and installation and operation of freezer alarms. The existence of this policy is not a guarantee that the University will always be able to respond to freezer alarms or be able to restore temperate conditions quickly enough to prevent damage.

This chapter discusses the unique properties of nanomaterials, solid superatomic materials with at least one dimension in the range of one to 100 nanometers. Subsequent sections discuss the potential safety and health concerns from nanomaterials (based on cell culture and animal studies), the routes of exposure, and guidance on how to prevent exposures to nanomaterials.