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While the purpose of research, scholarship, and education at the University of North Carolina at Chapel Hill is to ultimately share information and new knowledge, there are times when access to certain items, information, or laboratory spaces should be restricted for confidentiality, export compliance, national security, safety, and/or other security reasons. To that end, this policy establishes a framework for identifying export-controlled items, information, and research spaces.

This operating standard establishes the overall responsibility of Principal Investigators (PIs) in undertaking sponsored research projects and related components of those projects.

In accordance with all relevant ethical, legal, and regulatory obligations, the University has established this operating standard demonstrating the University's commitment to have all required compliance-related elements in place before expending funds.

The Proposal Dashboard within RAMSeS creates the University’s official record for each sponsored research project. The RAMSeS Internal Processing Form (IPF) is required for each research proposal of a grant, contract, or cooperative agreement and it is used to collect financial and compliance information and documentation needed for internal review and approval.

Management of sponsored research is a combined effort of the University of North Carolina System Office (UNC-SO), the University proper, the sponsors that provide their support to research efforts at the University, and the Principal Investigators (PIs) who spearhead the research itself. The Office of Sponsored Programs (OSP) considers the policies, regulations, and requirements issued by State, University, and Federal offices for every individual sponsored research project.

The University of North Carolina at Chapel Hill (UNC-CH) is committed to providing a safe and healthful environment for all persons associated with the University, including faculty, staff, students, visitors, and members of the Chapel Hill community.

Additional details about occupationally-acquired cases of parasitic infections, as well as recommendations for post exposure management, are provided elsewhere.1-3 Effective antimicrobial treatment is available for most parasitic infections.4 Immunocompromised persons should receive individualized counseling (specific to host and parasite factors) from their personal healthcare provider and their employer about the potential risks associated with working with live organisms.

Blastomyces dermatitidis is a dimorphic fungal pathogen existing in nature and in laboratory cultures at room temperature as a filamentous mold with asexual spores (conidia) that are the infectious particles; these convert to large budding yeasts under the appropriate culture conditions in vitro at 37°C and in the parasitic phase in vivo in warm-blooded animals. The sexual stage is an Ascomycete with infectious ascospores.

Bacillus anthracis, a gram-positive, non-hemolytic, and non-motile bacillus, is the etiologic agent of anthrax, an acute bacterial disease of mammals, including humans. Like all members of the genus Bacillus, under adverse conditions B. anthracis has the ability to produce spores that allow the organism to persist for long periods until the return of more favorable conditions.

Biological materials require specific packaging, labeling, and documentation. Infectious materials (materials containing or expected to contain pathogens affecting humans) are regulated by the US Department of Transportation (DOT) and the International Air Transport Association (IATA).

Resources for information, consultation, and advice on biohazard control, decontamination procedures, and other aspects of laboratory and animal safety management

Any shipment of radioactive materials from the University must be in full compliance with U.S. Department of Transportation, U.S. Nuclear Regulatory Commission and/or North Carolina requirements. These regulations are constantly changing. EHS maintains current copies, and the staff is trained and knowledgeable in their applications.

Nuclear gauge design incorporates operator safety as a prime consideration. However, as with any device containing radioactive materials, some general precautions must be observed.

Bone densitometers will be surveyed by the Radiation Safety staff at each source loading to ensure that anticipated exposure rates are not exceeded. All individuals using the devices will be registered with EHS as Radiation Workers. A trial period of personnel radiation monitoring may be put into effect.

This policy was created to ensure compliance with state and University regulations; establish guidelines for approval, control and accounting for employees and others who travel on University business; and ensure fairness for both the traveler and the University.