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While the purpose of research, scholarship, and education at the University of North Carolina at Chapel Hill is to ultimately share information and new knowledge, there are times when access to certain items, information, or laboratory spaces should be restricted for confidentiality, export compliance, national security, safety, and/or other security reasons. To that end, this policy establishes a framework for identifying export-controlled items, information, and research spaces.

The University of North Carolina at Chapel Hill (UNC-CH) is committed to providing a safe and healthful environment for all persons associated with the University, including faculty, staff, students, visitors, and members of the Chapel Hill community.

This Policy seeks to preserve the benefits of life sciences Dual Use Research of Concern (DURC) at the University while minimizing the risk that the knowledge, information, products, or technologies generated from such research could create the potential negative consequences identified in the Federal DURC Policy.

Resources for information, consultation, and advice on biohazard control, decontamination procedures, and other aspects of laboratory and animal safety management

The CDC and USDA have designated certain biological agents and toxins as Select Agents, because they have the potential to pose a severe threat to public, animal or plant health, or to animal or plant products. These materials require federal registration and approval to receive, posses, or transfer them.

Biological materials require specific packaging, labeling, and documentation. Infectious materials (materials containing or expected to contain pathogens affecting humans) are regulated by the US Department of Transportation (DOT) and the International Air Transport Association (IATA).

Additional details about occupationally-acquired cases of parasitic infections, as well as recommendations for post exposure management, are provided elsewhere.1-3 Effective antimicrobial treatment is available for most parasitic infections.4 Immunocompromised persons should receive individualized counseling (specific to host and parasite factors) from their personal healthcare provider and their employer about the potential risks associated with working with live organisms.

Blastomyces dermatitidis is a dimorphic fungal pathogen existing in nature and in laboratory cultures at room temperature as a filamentous mold with asexual spores (conidia) that are the infectious particles; these convert to large budding yeasts under the appropriate culture conditions in vitro at 37°C and in the parasitic phase in vivo in warm-blooded animals. The sexual stage is an Ascomycete with infectious ascospores.

Bacillus anthracis, a gram-positive, non-hemolytic, and non-motile bacillus, is the etiologic agent of anthrax, an acute bacterial disease of mammals, including humans. Like all members of the genus Bacillus, under adverse conditions B. anthracis has the ability to produce spores that allow the organism to persist for long periods until the return of more favorable conditions.

Nuclear gauge design incorporates operator safety as a prime consideration. However, as with any device containing radioactive materials, some general precautions must be observed.

Bone densitometers will be surveyed by the Radiation Safety staff at each source loading to ensure that anticipated exposure rates are not exceeded. All individuals using the devices will be registered with EHS as Radiation Workers. A trial period of personnel radiation monitoring may be put into effect.

Any shipment of radioactive materials from the University must be in full compliance with U.S. Department of Transportation, U.S. Nuclear Regulatory Commission and/or North Carolina requirements. These regulations are constantly changing. EHS maintains current copies, and the staff is trained and knowledgeable in their applications.

This chapter is an overview of the requirements for working with biological hazards. You can find more detailed information about working with biological hazards in the UNC Exposure Control Plan (Bloodborne Pathogens), the UNC Biological Safety Manual and on our website.

This chapter gives definitions and protocols for chemicals that are classified as controlled substances by the U.S. Drug Enforcement Administration. Controlled substances have special rules for acquisition, storage, security, inventory/recordkeeping, disposal, and importing or exporting, detailed in this chapter. The appendices include a current list of controlled substances and forms for inventory support and personnel screening.

This policy establishes requirements and best practices for international travel by faculty, staff, and students affiliated with the UNC-Chapel Hill Eshelman School of Pharmacy. It ensures compliance with U.S. laws, university regulations, and safeguards personal and institutional resources.