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This document provides guidance on conducting a risk assessment, implementing a risk mitigation program, communicating during and after the assessment, and developing practices to support ongoing application of the risk assessment process to ensure safe laboratory operations.

A comprehensive biosafety risk assessment is a key component of a successful biosafety program and should be part of an all-hazards risk assessment; it should be conducted on a continual basis to address evolving risks within the laboratory environment.

This chapter describes the containment principles of biological safety cabinets (BSCs), the various classes and types of BSCs and their uses, how to select the correct type of BSC for your needs, how to get approval for installation of a BSC, and their installation and certification requirements.